Keap1 also reversibly translocates for the p62-gels in a very p62-binding dependent vogue to activate the transcription variable Nrf2. Mice deficient for Atg8-interaction-dependent selective autophagy display that impaired turnover of p62-gels contributes to Nrf2 hyperactivation in vivo. These effects show that p62-gels will not be uncomplicated su